Government Aided Pharmacy College Permanently Affiliated To University Of Mumbai, Approved By AICTE DTE And PCI, Accreditated by National Board of Accreditation for B. Pharm program (2008-2013)

Only Pharmacy College in INDIA awarded Best Industry Linked Institute in Pharmacy Mentor category by AICTE-CII

MISSION

To educate and train students in the knowledge and practice of pharmaceutical sciences and to contribute to improvement of health of the society, through education and research programs.

VISION

To be a leader in Pharmacy Education, Pharmacy Training, and Research in Pharmaceutical Sciences.

Faculty of Pharmaceutical Analysis Department

Name of the Faculty: Dr. (Mrs.) Krishnapriya Mohanraj

Designation: Professor and Head, Department of Pharmaceutical Analysis

Email: krishnapriyamohanraj@gmail.com





Educational Qualifications:

Sr no. Degree University Year of Passing
1) B. Pharm C. U. Shah college of Pharmacy, SNDT women's University, Mumbai 1988
2) M. Pharm University Department of Chemical Technology, Mumbai 1990
3) Ph. D. (Tech) University Department of Chemical Technology, Mumbai 1998

Awards and Fellowships:(ALL)

Sr no. Award/Fellowship Year of Receipt
1) Received Special award for the oral presentation, Mayuri Pillai and Krishnapriya Mohanraj "Study of the forced degradation behavior of fenoxazoline hydrochloride", National Seminar on Emerging Trends in Analytical Sciences organised by Indian Society of Analytical Scientists (ISAS) Hyderabad Chapter, in association with CSIR-Indian institute of Chemical Technology (CSIR-IICT) at CSIR-I I C T, Hyderabad, India, November 27-28, 2013 2013
2) Dr. P. D. Sethi annual award 2012 – Certificate of Merit for paper Mahajan Anand, Kale Sandeep, Thaker Anil, Krishnapriya Mohanraj, "LC, LC-MS/MS studies for identification and characterization of degradation products of lamotrigine and establishment of mechanistic approach towards degradation", Journal of Chromatography and Related Technologies, 35(16), 2255-2271(2012) 2012
3) Selected for and received a grant of 3000 pounds in the Thrust area of Pharmaceutical Analysis under the aegis of UKIERI (UK India Education Research Initiative) Indo UK Staff Exchange Program to conduct "Train the Trainer” programs for faculty at Kingston University, United Kingdom and also get trained in sophisticated instrumental analysis and in vitro analysis there (2011-12 Award). 2012

Recent Publications:(Best Five in last five years)

Sr no. Paper Title Journal / Year / Vol / Page
1) Comparison of conventional and microwave assisted synthesis of Benzotriazole derivatives Indian Journal of Pharmaceutical Sciences, 76(1), 2014, 46-53
2) Study of olopatadine hydrochloride under ICH recommended stress conditions by LC, LC-MS/TOF for identification and characterization of degradation products Journal of Chromatography and Related Technologies, Volume 36, Issue 13, May 2013, 1881-1898
3) LC, LC-MS/MS studies for the identification and characterization of degradation products of hydrochlorothiazide and establishment of mechanistic approach towards degradation Society, 23(3), 2012, 445-452
4) LC, LC-MS/MS studies for identification and characterization of degradation products of lamotrigine and establishment of mechanistic approach towards degradation (Awarded 8th P D Sethi Annual Award – Certificate of Merit -2013.) Journal of Chromatography and Related Technologies, 35(16), 2012, 2255-2271
5) What is the degradation product of ezetimibe? Journal of Pharmaceutical and Biomedical Analysis, Vol. 55, 2011, 1237-8

Recent Patents:

Sr no. Patent Title Patent Number
1) Krishnapriya Mohanraj, Akamanchi K.G., Dahanukar S.A., Rege NN, and Thatte UM. "A process for manufacturing highly active antiplatelet fraction from Neem leaf" IndianPatent No. 187690 of 17.11.2000

Recent Presentations: (last 3 years but not more than 5)

Sr no. Presentation Title Conference Details
1) Study of the forced degradation behavior of fenoxazoline hydrochloride (Awarded special prize for appreciation for oral presentation) National Seminar on Emerging Trends in Analytical Sciences organised by Indian Society of Analytical Scientists (ISAS) Hyderabad Chapter, in association with CSIR-Indian institute of Chemical Technology (CSIR-IICT) at CSIR-I I C T, Hyderabad, India, November 27-28, 2013.
2) Liquid chromatographic separation of cloperastine enantiomers using sulphated beta cyclodextrin as chiral mobile phase additive National Seminar on Emerging Trends in Analytical Sciences organised by Indian Society of Analytical Scientists (ISAS) Hyderabad Chapter, in association with CSIR-Indian institute of Chemical Technology (CSIR-IICT) at CSIR-I I C T, Hyderabad, India, November 27-28, 2013.
3) Development of stability indicating method for Tapentadol hydrochloride DST- ICMR sponsored National Symposium on “Multidisciplinary Research in Biomedical and Applied Sciences” at the School of Science, SVKM’s NMIMS, on the occasion of the National Education Day, scheduled on 11th & 12th November, 2013.
4) Enantiomeric separation of zopiclone using chiral mobile phase additive DST- ICMR sponsored National Symposium on “Multidisciplinary Research in Biomedical and Applied Sciences” at the School of Science, SVKM’s NMIMS, on the occasion of the National Education Day, scheduled on 11th & 12th November, 2013.
5) Design of benzotriazole based multi-targeted antifungal agents Conference on recent advances in Computational drug design at Indian Institute of Science, Bangalore on 16th -17th September, 2013

Expertise:

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Isolation, characterization and evaluation of bioactive constituents from herbal extracts using bioactivity guided fractionation.

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Computer aided Drug Design (in silico analysis), synthesis and pharmacological evaluation (in vitro analysis)

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Resolution of drugs, including enzymatic resolution and its monitoring.

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Chiral chromatography

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Forced degradation studies, Impurity profiling and development of stability indicating assays.

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Analytical method development and validation

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Synthesis, purification and characterization of impurities/metabolites.

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Structural Elucidation using spectroscopic techniques

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Bioanalytical method development and validation; Therapeutic Drug Monitoring

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Drug metabolism and pharmacokinetic analysis

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Herbal Analysis

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In vitro analysis for antibacterial, antifungal and antiamoebic activity

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Name of the Faculty: Dr.Vaishali A Shirsat

Designation: Associate Professor in Pharmaceutical Analysis

Email: vashirsat@bcpindia.org

Teaching Fields: Modern Pharmaceutical Analysis, Analytical method development & Validation techniques, Structure elucidation using modern analytical methods





Educational Qualifications:

Sr no. Degree University Year of Passing
1) Ph. D. (Tech) SNDT, Mumbai 2001
2) M. Pharm. SNDT, Mumbai 1994
3) B. Pharm. Pune University 1992

Awards and Fellowships:(ALL)

Sr no. Award/Fellowship Year of Receipt
1) Best Poster award- 'Phenotyping of CYP2C9 in sample Mumbai population using flurbiprofen as a probe drug', adjudged as first amongst the posters presented in the UGC Sponsored National Conference on Recent Trends in Biosciences & Applications in Industry held at K.J.Somaiya College of Science & Commerce, Mumbai 2008
2) ‘Phenotyping for CYP2A6, CYP2C9, CYP2D6, CYP2E1, FMO and N-acetyl transferase activities in a sample Mumbai population’, was adjudged as one amongst the top three posters at the Second International Symposium on Drug Metabolism and Pharmacokinetics Symposium: Applications towards Drug Discovery and Development’, held at NIPER, Mohali, India. 2010
3) Best Poster presentation award: ‘Stability Indicating Assay method for simultaneous estimation of Dutasteride and Tamsulosin hydrochloride’, for “Research - The Young Scientist” in First AAPS-NUS-BCP Regional Conference, on held at Bombay College of Pharmacy, Mumbai. 2010
4) Nominated for P.C.Dandiya Award ‘Gastroprotective activity of fenugreekseeds: An in vitro, in vivo and in silico approach’ at IPSCON-2012, 45thAnnual Conference of Indian Pharmacological Society and International Conference on 'Navigating Pharmacology towards Safe and EffectiveTherapy' to be held at Nagpur on January 04-07, 2013, organized by Smt. KishoritaiBhoyar College of Pharmacy, Kamptee, Nagpur. 2012

Recent Publications:(Best Five in last five years)

Sr no. Paper Title Journal / Year / Vol / Page
1) MS/MS and HPLC characterization of forced degradation products of Dutasteride and Tamsulosin hydrochloride. International Journal of Pharmaceutical Sciences and Research, 2014; 5(7): 2791-2806.
2) Identification of potential antioxidants by in-vitro activity guided fractionation of Bergenialigulata. Pharmacognosy Magazine, 2008; 4 (15): S78 – S84.
3) A New convenient, cheap and Industrially feasible method for the synthesis of an important intermediate of Benazepril. Indian Drugs, 2007; 44(2): 91 – 94.
4) High Performance Liquid Chromatographic determination of Sumatriptan succinate from pharmaceutical preparation. Indian Drugs, 1998; 35(7): 404 - 407.
5) Analysis of Felodipine in Tablets by HPLC. Indian Drugs, 1995; 32(5): 215 - 216.

Recent Patents:

Sr no. Presentation Title(Best Five in last five years) Conference Details
1) Composition for Prolonged Release of Drugs, Published in Indian Patent Patent Application No-1668/Mum/2009. Final Indian Patent filed: (No.E-2/1038/2010) Published in Indian Patent Journal on 21st Jan 2012.

Recent Presentations: (Best Five in last five years)

Sr no. Presentation Title(Best Five in last five years) Conference Details
1) Evaluation of Quercetin Prodrug for Antiangiogenesis activity. Avishkar 2013-14 Jan 2014, Mumbai University.
2) PEGylatedDocetaxelconjugate as a tumour specific therapeutic agent. Avishkar 2013-14 Jan 2014, Mumbai University.
3) In-vitro, In-vivo and In-silico analysis of fenugreek seed extracts for treating gastric ulcers Avishkar 2013-14 Jan 2014, Mumbai University.
4) “Gastroprotective activity of Fenugreek seeds: An invitro, in vivo and in silico approach” 45th Annual Conference of Indian Pharmacological Societyand International Conference on “Navigating Pharmacology towards Safe andEffective Therapy.”, Nagpur 5th – 7th January 2013
5) Stability indicating assay method for simultaneous estimation of Dutasteride and Tamsulosin Hydrochloride First AAPS-NUS-BCP regional conference on 25th February, 2010 at Bombay College of Pharmacy

Collaborations: (in current year)

Sr no. Title Industry/institute
Industrial
1) Development of suitable mobile phase for estimation of glycine by HPLC-Fluorescence method. Marico Ltd.
Academic
1) Confidential NAIR hospital
2) Confidential Kingston University,
3) Confidential Mumbai Veterinary College

Consultancy Services:(in last five years)

Sr no. Title Industry/institute
1) Development of suitable mobile phase for estimation of glycine by HPLC-Fluorescence method. Marico Ltd.

Research Area and interest:

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Development & Validation of analytical methods for assay of drugs and drug intermediates.

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Forced degradation studies and Development & Validation of stability indicating assays.

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Synthesis of polymer derivatives.

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Bioactivity guided fractionation of herbals.

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Formulation development.

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Bioanalytical method development and validation.

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PEGylation of anticancer drug molecules.


Expertise and instrumental/research facilities you can provide to interested parties:

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HPLC method development and analysis using UV/Fluorescence/PDA detector.

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