Dr. (Mrs.) Vaishali A Shirsat
Dr. (Mrs.) Krishnapriya Mohanraj
Name of the Faculty: Dr.Vaishali A Shirsat
Designation: HOD-Associate Professor in Pharmaceutical Analysis
Email: vaishali.shirsat@bcp.edu.in
Teaching Fields: Modern Pharmaceutical Analysis, Analytical method development
& Validation techniques, Structure elucidation using modern analytical methods
Educational Qualifications:
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Sr no.
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Degree
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University
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Year of Passing
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1)
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Ph. D. (Tech)
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SNDT, Mumbai
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2001
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2)
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M. Pharm.
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SNDT, Mumbai
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1994
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3)
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B. Pharm.
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Pune University
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1992
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Awards and Fellowships:(ALL)
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Sr no.
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Award/Fellowship
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Year of Receipt
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1)
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Best Poster award- 'Phenotyping of CYP2C9 in sample Mumbai population using flurbiprofen
as a probe drug', adjudged as first amongst the posters presented in the UGC Sponsored
National Conference on Recent Trends in Biosciences & Applications in Industry held
at K.J.Somaiya College of Science & Commerce, Mumbai
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2008
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2)
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‘Phenotyping for CYP2A6, CYP2C9, CYP2D6, CYP2E1, FMO and N-acetyl transferase activities
in a sample Mumbai population’, was adjudged as one amongst the top three posters
at the Second International Symposium on Drug Metabolism and Pharmacokinetics Symposium:
Applications towards Drug Discovery and Development’, held at NIPER, Mohali, India.
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2010
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3)
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Best Poster presentation award: ‘Stability Indicating Assay method for simultaneous
estimation of Dutasteride and Tamsulosin hydrochloride’, for “Research - The Young
Scientist” in First AAPS-NUS-BCP Regional Conference, on held at Bombay College
of Pharmacy, Mumbai.
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2010
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4)
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Nominated for P.C.Dandiya Award ‘Gastroprotective activity of fenugreekseeds: An
in vitro, in vivo and in silico approach’ at IPSCON-2012, 45thAnnual Conference
of Indian Pharmacological Society and International Conference on 'Navigating Pharmacology
towards Safe and EffectiveTherapy' to be held at Nagpur on January 04-07, 2013,
organized by Smt. KishoritaiBhoyar College of Pharmacy, Kamptee, Nagpur.
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2012
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Recent Publications:(Best Five in last five years)
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Sr no.
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Paper Title
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Journal / Year / Vol / Page
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1)
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MS/MS and HPLC characterization of forced degradation products of Dutasteride and
Tamsulosin hydrochloride.
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International Journal of Pharmaceutical Sciences and Research, 2014; 5(7): 2791-2806.
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2)
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Identification of potential antioxidants by in-vitro activity guided fractionation
of Bergenialigulata.
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Pharmacognosy Magazine, 2008; 4 (15): S78 – S84.
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3)
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A New convenient, cheap and Industrially feasible method for the synthesis of an
important intermediate of Benazepril.
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Indian Drugs, 2007; 44(2): 91 – 94.
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4)
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High Performance Liquid Chromatographic determination of Sumatriptan succinate from
pharmaceutical preparation.
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Indian Drugs, 1998; 35(7): 404 - 407.
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5)
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Analysis of Felodipine in Tablets by HPLC.
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Indian Drugs, 1995; 32(5): 215 - 216.
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Recent Patents:
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Sr no.
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Presentation Title(Best Five in last five years)
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Conference Details
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1)
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Composition for Prolonged Release of Drugs, Published in Indian Patent
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Patent Application No-1668/Mum/2009. Final Indian Patent filed: (No.E-2/1038/2010)
Published in Indian Patent Journal on 21st Jan 2012.
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Recent Presentations: (Best Five in last five years)
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Sr no.
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Presentation Title(Best Five in last five years)
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Conference Details
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1)
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Evaluation of Quercetin Prodrug for Antiangiogenesis activity.
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Avishkar 2013-14 Jan 2014, Mumbai University.
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2)
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PEGylatedDocetaxelconjugate as a tumour specific therapeutic agent.
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Avishkar 2013-14 Jan 2014, Mumbai University.
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3)
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In-vitro, In-vivo and In-silico analysis of fenugreek seed extracts for treating
gastric ulcers
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Avishkar 2013-14 Jan 2014, Mumbai University.
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4)
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“Gastroprotective activity of Fenugreek seeds: An invitro, in vivo and in silico
approach”
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45th Annual Conference of Indian Pharmacological Societyand International Conference
on “Navigating Pharmacology towards Safe andEffective Therapy.”, Nagpur 5th – 7th
January 2013
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5)
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Stability indicating assay method for simultaneous estimation of Dutasteride and
Tamsulosin Hydrochloride
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First AAPS-NUS-BCP regional conference on 25th February, 2010 at Bombay College
of Pharmacy
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Collaborations: (in current year)
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Sr no.
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Title
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Industry/institute
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Industrial
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1)
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Development of suitable mobile phase for estimation of glycine by HPLC-Fluorescence
method.
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Marico Ltd.
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Academic
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1)
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Confidential
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NAIR hospital
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2)
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Confidential
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Kingston University,
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3)
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Confidential
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Mumbai Veterinary College
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Consultancy Services:(in last five years)
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Sr no.
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Title
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Industry/institute
|
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1)
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Development of suitable mobile phase for estimation of glycine by HPLC-Fluorescence
method.
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Marico Ltd.
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Research Area and interest:
»
Development & Validation of analytical methods for assay of drugs and drug intermediates.
»
Forced degradation studies and Development & Validation of stability indicating
assays.
»
Synthesis of polymer derivatives.
»
Bioactivity guided fractionation of herbals.
»
Formulation development.
»
Bioanalytical method development and validation.
»
PEGylation of anticancer drug molecules.
Expertise and instrumental/research facilities you can provide to interested parties:
»
HPLC method development and analysis using UV/Fluorescence/PDA detector.
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Name of the Faculty: Dr. (Mrs.) Krishnapriya Mohanraj
Designation: Professor, Department of Pharmaceutical Analysis
Email: krishnapriyamohanraj@gmail.com
Educational Qualifications:
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Sr no.
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Degree
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University
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Year of Passing
|
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1)
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B. Pharm
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C. U. Shah college of Pharmacy, SNDT women's University, Mumbai
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1988
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2)
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M. Pharm
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University Department of Chemical Technology, Mumbai
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1990
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3)
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Ph. D. (Tech)
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University Department of Chemical Technology, Mumbai
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1998
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Awards and Fellowships:(ALL)
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Sr no.
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Award/Fellowship
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Year of Receipt
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1)
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a. Co Chairperson of the Board of Studies for Pharmacy at the
Dr B R Ambedkar Technological University, Maharashtra.
b. Member, Board of Studies for MSc Bioanalytical Sciences
and Integrated MSc Bioanalytical Sciences, Ramnarain Ruia College of Arts and Science, Mumbai.
c. Expert for external audit (Academic teaching and learning) of
Dr. Bhanuben Nanavati College of Pharmacy under IQAC cell.
d. Member of B.Pharm/ B.Tech Pharma syllabus revision committee for Institute of Chemical Technology.
e. Chairperson for framing New syllabus for Mumbai University for the courses of Pharmaceutical Analysis
and Quality Assurance at the Master in Pharmacy program
f. Judge for Best Oral Presentation for PhD Research Day, School of Pharmacy and Chemistry, Kingston University, London.
g. Member of Board of Studies for Pharmaceutical Chemistry and Pharmaceutical Analysis at SVKM’s NMIMS University.
h. Member of the Research Advisory Committee and Thesis Advisory Committee for PhD Projects at SVKM’s NMIMS University
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2017 onwards
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2)
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1st prize for oral presentation at 8th Indian Youth Science Congress on 16-18
February 2017 for oral presentation. Under category Science and Technology
Pranav Pathak*, Krishnapriya Mohanraj, Laboratory synthesized Chiral selector
and Core-shell Technology – Boon for Chiral separations
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2017
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3)
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2nd prize at Inter collegiate Avishkar 2016-2017 on 20 December 2016 for poster
and oral presentation and participated (poster and oral presentation) at
Inter-University Avishkar research convention at Nanded, Maharashtra 27-29 January 2017.
Under category Medicine and Pharmacy, Level- PPG Pranav Pathak*, Krishnapriya Mohanraj,
Simple and Cost-effective Enantioseparation of Chiral Drugs Using Chiral Mobile
Phase Additives and Core-shell Technology
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2016
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4)
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Received Prof ML Khorana award for best paper in medicinal and synthetic Chemistry
in Indian Journal of Pharmaceutical Sciences for 2014, conferred by Indian Pharmaceutical Association
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2016
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5)
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Received Special award for the oral presentation, Mayuri Pillai and Krishnapriya
Mohanraj "Study of the forced degradation behavior of fenoxazoline hydrochloride",
National Seminar on Emerging Trends in Analytical Sciences organised by Indian Society
of Analytical Scientists (ISAS) Hyderabad Chapter, in association with CSIR-Indian
institute of Chemical Technology (CSIR-IICT) at CSIR-I I C T, Hyderabad, India,
November 27-28, 2013
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2013
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6)
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Dr. P. D. Sethi annual award 2012 – Certificate of Merit for paper Mahajan Anand,
Kale Sandeep, Thaker Anil, Krishnapriya Mohanraj, "LC, LC-MS/MS studies for identification
and characterization of degradation products of lamotrigine and establishment of
mechanistic approach towards degradation", Journal of Chromatography and Related
Technologies, 35(16), 2255-2271(2012)
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2012
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7)
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Selected for and received a grant of 3000 pounds in the Thrust area of Pharmaceutical
Analysis under the aegis of UKIERI (UK India Education Research Initiative) Indo
UK Staff Exchange Program to conduct "Train the Trainer” programs for faculty at
Kingston University, United Kingdom and also get trained in sophisticated instrumental
analysis and in vitro analysis there (2011-12 Award).
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2012
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Recent Publications:(Best Five in last five years)
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Sr no.
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Paper Title
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Journal / Year / Vol / Page
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1)
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Separation, Identification and Characterization of Degradation Products of Erlotinib
Hydrochloride under ICH Recommended Stress Conditions by LC, LC-MS/TOF
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Journal of Liquid Chromatography & Related Technologies, 2015, 38(5), 629-639.
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2)
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Chiral separation of citalopram by reversed phase HPLC using sulfated beta
cyclodextrin as chiral mobile phase additive
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International Journal of Pharmacy and Pharmaceutical Sciences, May 2015,
Vol 7, Issue 6, 306-310
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3)
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Design, synthesis and evaluation of benzotriazole derivatives as novel antifungal agents
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Bioorganic and Medicinal Chemistry Letters, June 2015, 25(17), 3730-7
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4)
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Development of collateral vessels: A new paradigm in CAM angiogenesis model
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Microvascular Research, 103 (2015) 11–13.
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5)
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Comparison of conventional and microwave assisted synthesis of Benzotriazole derivatives
Awarded Prof M L Khorana award for best paper in Medicinal and Synthetic Chemistry
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Indian Journal of Pharmaceutical Sciences, 76(1), Jan 2014, 46-53
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Recent Patents:
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Sr no.
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Patent Title
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Patent Number
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1)
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Krishnapriya Mohanraj, Akamanchi K.G., Dahanukar S.A., Rege NN, and Thatte UM. "A
process for manufacturing highly active antiplatelet fraction from Neem leaf"
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IndianPatent No. 187690 of 17.11.2000
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Recent Presentations: (last 3 years but not more than 5)
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Sr no.
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Presentation Title
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Conference Details
|
|
1)
|
Pranav Pathak*, Krishnapriya Mohanraj, Laboratory synthesized Chiral selector
and Core-shell Technology – Boon for Chiral separations,
(1st prize under category Science and Technology)
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8th Indian Youth Science Congress on 16-18 February 2017 for oral presentation
|
|
2)
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Pranav Pathak*, Krishnapriya Mohanraj, Simple and Cost-effective Enantioseparation
of Chiral Drugs Using Chiral Mobile Phase Additives and Core-shell Technology,
(Won 2nd prize Under category Medicine and Pharmacy, Level- PPG, Mumbai University)
|
Inter collegiate Avishkar 2016-2017 on 20 December 2016 for poster and oral presentation
and participated (poster and oral presentation) at Inter-University Avishkar research
convention at Nanded, Maharashtra 27-29 January 2017
|
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3)
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Kratika Richhariya*, Madhura Chaudhari, Harshita Dhimar, Krishnapriya Mohanraj,
Bioanalysis of S-methyl N, N-diethyldithiocarbamate (MeDDC), a metabolite of
Disulfiram for therapeutic drug monitoring of Disulfiram
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Presented poster at Inter collegiate Avishkar 2016-17,
Under category Medicine and Pharmacy, Level- PG
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4)
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Prachiti Mankar*, Jay Shah, Krishnapriya Mohanraj, Antimicrobial susceptibility
screening of novel benzotriazole derivatives by Resazurin Microtitre Assay (REMA)
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Presented poster at Inter collegiate Avishkar 2016-17,
Under category Medicine and Pharmacy, Level- PG
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5)
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Vipul Suryavanshi, Mehraram Patel, Nagesh Sandu, Saurabh Chhatre and Krishnapriya Mohanraj
Resazurinmicrotitre assay (REMA) for antibacterial and antifungal activity of herbs of
three antidiarrhoeal formulations: Bilagyl® and Berbenterone® tablets and Berbenterone® suspension
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3rd International Conference and Exhibition on Pharmacognosy, Phytochemistry &
Natural Products, Hyderabad, India, October 26-28, 2015
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Collaborations: (in last five years)
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Sr no.
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Title
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Industry/institute
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1)
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2 projects (details below)
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Nerliker Hospital, Nasik
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2)
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1 project (details below)
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S G Pharma
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3)
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LC-MS-MS Analysis
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SPP School of Pharmacy and Technology Department
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Technology Transfer, Projects and Consultancy Services: (in last five years)
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Sr no.
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Title
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Industry/institute
|
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1)
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Bioanalysis of Disulfiram and Its Metabolites By HPLC
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Nerliker Hospital, Nasik
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2)
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LC-MS/MS Analysis of Disulfiram and Its Metabolite
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Nerliker Hospital, Nasik
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3)
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HPLC Analysis of Quantification of Chlorobutanol in Chlorpheniramine Maleate Injection
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SG Pharma
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4)
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Technology Transfer for Synthesis of a Chiral Selector
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LOBA Chemie
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5)
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In Vitro Studies of Bilagyl, Berbenterone Tablets and Berbenterone Paediatric
Suspension for Anti Amoebic, Antibacterial and Antifungal Activity for Proof
of Concept in Infectious Diarrhoea Therapy
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Sandu Pharmaceuticals Ltd
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6)
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HPLC Analysis of some Intermediates
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Ambernath Organics
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7)
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Stability Studies of an Intermediate and its Monitoring by HPLC
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Ambernath Organics
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8)
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Consultancy Assignment
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GlaxoSmithKline
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9)
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One-day special Technical Development Program on ‘Mass Spectrometry and LC-MS-MS’
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Analytical Solutions
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10)
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Series of half day Training programs
a. HPLC method development and validation
b. GC method development
c. 1H NMR spectroscopy:
Part 1- Theory and Chemical Shift
Part 2- Splitting pattern and coupling constant
Part 3- Non-first order spectra
d. Spectral interpretation – Structural elucidation problems
e. Mass spectrometry-
f. 2D NMR spectroscopy- COSY and HETCOR
g.13C NMR spectroscopy-DEPT and APT
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Aarti Health Care Pvt Ltd
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Research Area and interest:
»
Isolation, characterization and evaluation of bioactive constituents from herbal
extracts using bioactivity guided fractionation.
»
Computer aided Drug Design (in silico analysis), synthesis and pharmacological evaluation
(in vitro analysis)
»
Resolution of drugs, including enzymatic resolution and its monitoring.
»
Chiral chromatography
»
Forced degradation studies, Impurity profiling and development of stability indicating
assays.
»
Analytical method development and validation
»
Synthesis, purification and characterization of impurities/metabolites.
»
Structural Elucidation using spectroscopic techniques
»
Bioanalytical method development and validation; Therapeutic Drug Monitoring
»
Drug metabolism and pharmacokinetic analysis
»
Herbal Analysis
»
In vitro analysis for antibacterial, antifungal and antiamoebic activity
Expertise and instrumental/research facilities you can provide to interested parties:
»
Instrumental facilities:
»
1. HPLC
»
2. FTIR
»
3. LCMSMS (Triple quadrupole and ion trap)
»
4. HPTLC and HPTLC-MS
»
5. ICP-MS
»
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